Effective Depletion of Regulatory T Cells Allows the Recruitment of Mesothelin‐Specific CD8+ T Cells to the Antitumor Immune Response Against a Mesothelin‐Expressing Mouse Pancreatic Adenocarcinoma

Effective Depletion of Regulatory T Cells Allows the Recruitment of Mesothelin‐Specific CD8+ T Cells to the Antitumor Immune Response Against a Mesothelin‐Expressing Mouse Pancreatic Adenocarcinoma

Source :

• Clinical and Translational Science [ 1752-8054 ] ; 2008-12.

English descriptors

• Teeft :
  • Amino acid, Antitumor, Antitumor activity, Axillary lymph nodes, Black line, Cancer patients, Carneiro, Cell depletion, Cell lines, Cell permeabilization, Cell responses, Clin cancer, Combinatorial, Combinatorial approach, Control peptide, Cyclophosphamide, Cytometry, Data points, Days post vaccination, Depleting tregs, Depletion, Differentiation antigen, Effective antitumor, Effector, Effector function, Entire mesothelin protein, Epitope, Facs buffer, Flow cytometric analysis, Flow cytometry, Further evaluation, Gray line, Hind limb, Humidified atmosphere, Immune, Immune response, Immune system, Immune tolerance, Immunization, Immunodominant epitopes, Immunol, Immunol methods, Immunotherapy, Intracellular staining, Irrelevant peptide, Jaffee, Johns hopkins university, Kinetic profile, Licensing agreement, Life technologies, Lymph nodes, Lymphocyte, Mammary tumors, Mesothelin, Mesothelin epitopes, Mesothelin expression, Mice vaccinated, Mock vaccine, Monoclonal antibody, Mouse, Mouse models, Multiple mechanisms, Murine, Ovarian cancers, Pancreatic, Pancreatic cancer, Pancreatic cancers, Peptide, Peripheral blood, Peripheral tolerance, Previous studies, Proc natl acad, Regulatory, Regulatory cell depletion, Regulatory cells, Relevant peptide, Representative experiment, Right flank, Room temperature, Semin immunol, Similar results, Single agents, Specific peptide, Spleen, Splenocytes, Subcutaneous injections, Survival curves, Target antigen, Target cells, Total number, Total population, Treg, Treg cell depletion, Treg cells, Treg depletion, Tregs, Tumor, Tumor antigens, Tumor cells, Tumor challenge, Tumor clearance, Tumor immunity, Tumor inoculation, Tumor model, Tumor rejection, Tumor vaccine, Vaccination, Vaccine, Vaccine approach, Vaccine approaches, Vaccine efficacy, Vaccine treatment, Vivo.

Abstract

• https://api.istex.fr/ark:/67375/WNG-BB6LS5Q2-2/fulltext.pdf

Affiliations:

• États-Unis
• Maryland

Links toward previous steps (curation, corpus...)

• to stream Istex, to step Corpus: 000178
• to stream Istex, to step Curation: 000178

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Istex/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000803 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Istex/Checkpoint/biblio.hfd -nk 000803 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    MersV1
   |flux=    Istex
   |étape=   Checkpoint
   |type=    RBID
   |clé=     ISTEX:237572302112A935F98DA47984194D457312F603
   |texte=   Effective Depletion of Regulatory T Cells Allows the Recruitment of Mesothelin‐Specific CD8+ T Cells to the Antitumor Immune Response Against a Mesothelin‐Expressing Mouse Pancreatic Adenocarcinoma
}}

This area was generated with Dilib version V0.6.33. Data generation: Mon Apr 20 23:26:43 2020. Site generation: Sat Mar 27 09:06:09 2021